For Bacterial Artificial Chromosome (Bac) we have terms and definitions in 3 topics. The topics are Bioinformatics, Genome and Microbiology.

Bacterial Artificial Chromosome (Bac) (Bioinformatics)

Cloning vector that can incorporate large fragments of DNA. (see YACS)

Bacterial Artificial Chromosome (Bac) (Genome)

A vector used to clone DNA fragments (100- to 300-kb insert size; average, 150 kb) in Escherichia coli cells. Based on naturally occurring F-factor plasmid found in the bacterium E. coli.
See also: cloning vector

Bacterial Artificial Chromosome (Bac) (Microbiology)

A chromosome-like structure, constructed by genetic engineering. BAC is a cloning vector capable of carrying between 100 and 300 kilobases of target sequence. They are propagated as a mini-chromosome in a bacterial host. The size of the typical BAC is ideal for use as an intermediate in large-scale genome sequencing projects. Entire genomes can be cloned into BAC libraries, and entire BAC clones can be shotgun-sequenced fairly rapidly.

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