For Binding Site we have terms and definitions in 4 topics. The topics are HIV and AIDs, Microbiology, Psychoactives and Yeast Genome.

Binding Site (HIV and AIDs)

An area where two protein molecules join together. For example, CYTOKINES bind to CELL SURFACE RECEPTORS and the GP120 PROTEIN of HIV binds to the CD4 CELL SURFACE RECEPTOR.

Binding Site (Microbiology)

A place on cellular DNA to which a protein (such as a transcription factor) can bind. Typically, binding sites might be found in the vicinity of genes, and would be involved in activating transcription of that gene (promoter elements), in enhancing the transcription of that gene (enhancer elements), or in reducing the transcription of that gene (silencers). NOTE that whether the protein in fact performs these functions may depend on some condition, such as the presence of a hormone, or the tissue in which the gene is being examined. Binding sites could also be involved in the regulation of chromosome structure or of DNA replication.

Binding Site (Psychoactives)

1. A location on a receptor or other structure where a given chemical attaches itself.

Binding Site (Yeast Genome)

Consensus sequence to which a specific molecule binds.

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