For Histone Acetyltransferases we have a term and definition in Huntingtons Disease.

Histone Acetyltransferases (Huntingtons Disease)

These enzymes add an acetyl group to histones, thus releasing the restricted access to DNA imposed by histones. Transcription factors can then bind to the DNA, allowing gene transcription to occur. Patients with HD tend to have decreased histone acetyltransferase activity.

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