Topical Terminology  

       

Topical Terminology > Reading Frame



2 Definitions

Reading frame

For Reading frame we have terms and definitions in 2 topics. The topics are Bioinformatics and Microbiology.



Reading Frame (Bioinformatics)

A sequence of codons beginning with an intiation codon and ending with a termination codon, typically of at least 150 bases (50 amino acids) coding for a polypeptide or protein chain (see ORF and URF).


Reading Frame (Microbiology)

When mRNA is translated by the cell, the nucleotides are read three at a time. By starting at different positions, the groupings of three that are produced can be entirely different. The following example shows a DNA sequence and the three reading frames in which it could be read. Not only is an entirely different amino acid sequence specified by the different reading frames, but two of the three frames have stop codons, and thus are not open reading frames (asterisks indicate a stop codon).




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