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Topical Terminology > E-map



1 Definition

e-map

For e-map we have a term and definition in Yeast Genome.



E-map (Yeast Genome)

Epistatic Mini Array Profile. A method that creates and quantifies high density genetic interaction maps. In this method, observed double mutant colony sizes are compared to those that would be expected from a distribution of typical double mutant colonies of each strain. Each interaction is assigned a score which indicates the magnitude of the difference from the expected value and the certainty of the score. A negative (or aggravating) score < -3 would imply synthetic sick/lethal interaction and a positive (alleviating) score > +3 would imply suppressor interaction (Schuldiner M, et al. (2005)).




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