Topical Terminology > Uorf
uORF
For uORF we have a term and definition in Yeast Genome.
Uorf (Yeast Genome) 
Small upstream open reading frame (uORF) that precedes the major open reading frame (ORF). uORFs usually inhibit downstream translation by blocking ribosomal scanning to promote efficient termination. In some cases, uORFs stimulate translation of the major ORF by allowing scanning ribosomal subunits to proceed via leaky scanning and reinitiation to the major ORF.
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